Kant's critical philosophy marks the end of a two-thousand year tradition of metaphysics. Against this older tradition, Kant proposes a new metaphysics of knowledge and human freedom with the autonomy of the subject as its principle. Led by the principle of subjectivity, it attempts to obtain a unified understanding of the whole world organized into a system of reason. In this way, the idea of classical metaphysics receives a new controversial interpretation still discussed today. In twelve contributions, the fifth volume (...) of the Yearbook pursues the different forms of grounding metaphysics after Kant. (shrink)

My work is concerned mainly with an abstract subject: the problem of human knowledge and, in particular, of scientific knowledge.I am an optimist. I am an optimist in a world where among the intelligentsia it has become a strict rule that one must be a pessimist if one wants to be “in”. But I do believe that our age is not so bad as is generally maintained; I do believe that it is better and more beautiful than its reputation. A (...) quarter of a century ago, I gave a lecture, the title of which sounds today even more provocative than it did then: “The History of our Time: An Optimist's View”. (shrink)

In this study the theory of risk factors is discussed. The risk-concept is essential in cardiology and is, furthermore, important not only in medicine in general, but also and particularly in ecology. Since environmental risk factors endanger our health, ecological risks have to be taken as medical problems. If a factor or a set of factors is a necessary but not a sufficient condition for a disease we speak of a risk factor or of risk factors. Statistical analysis of risk (...) factors can be performed by multivariate methods. A method which is particularly useful for finding the most important of a set of risk factors, is discriminant analysis. (shrink)

Kant's critical philosophy marks the end of a two-thousand year tradition of metaphysics. Against this older tradition, Kant proposes a new metaphysics of knowledge and human freedom with the autonomy of the subject as its principle. Led by the principle of subjectivity, it attempts to obtain a unified understanding of the whole world organized into a system of reason. In this way, the idea of classical metaphysics receives a new controversial interpretation still discussed today. In twelve contributions, the fifth volume (...) of the Yearbook pursues the different forms of grounding metaphysics after Kant. (shrink)

In recent years, a number of groups have begun to argue that pension funds have an obligation to invest their capital in socially responsible ways. The concept of social investing of pension funds is examined with regard to legal requirements, determination of social objectives, measurement of perfornance, and financial effects. This analysis concludes that, while the problems of social investing are relatively well-defined, the benefits are nebulous. A social-oriented investment strategy should be adopted only after a careful review of all (...) factors. (shrink)

Kants Vernunftkritik hat das Wissen zugunsten des Glaubens aufgehoben. Angeregt vor allem durch F.H. Jacobi, wird das Verhältnis von Glauben und Vernunft in der Philosophie nach Kant erneut zu einem zentralen Thema. Zur Entscheidung stehen die Fragen, ob der Glaube das Fundament von Wissen sein kann, ob der Glaube eine Grenze der Vernunft markiert oder ob eine absolut ges.

Over the past decades, great strides have been made to professionalize and increase access to transgender medicine. As the evidence base grows and conceptualizations regarding gender dysphoria/gender incongruence evolve, so too do ideas regarding what constitutes good treatment and decision-making in transgender healthcare. Against this background, differing care models arose, including the ‘Standards of Care’ and the so-called ‘Informed Consent Model’. In these care models, ethical notions and principles such as ‘decision-making’ and ‘autonomy’ are often referred to, but left unsubstantiated. (...) This not only transpires into the consultation room where stakeholders are confronted with many different ethical challenges in decision-making, but also hampers a more explicit discussion of what good decision-making in transgender medicine should be comprised of. The aim of this paper is to make explicit the conceptual and normative assumptions regarding decision-making and client autonomy underpinning the ‘Standards of Care’ and ‘Informed Consent Model’ currently used in transgender care. Furthermore, we illustrate how this elucidation aids in better understanding stakeholders’ ethical challenges related to decision-making. Our ethical analysis lays bare how distinct normative ambiguities in both care models influence decision-making in practice and how foregrounding one normative model for decision-making is no moral panacea. We suggest that the first steps towards good decision-making in gender-affirming medical care are the acknowledgement of its inherent normative and moral dimensions and a shared, dialogical approach towards the decision-making process. (shrink)